Collectively, these observations highlight a convergent pathogenic mechanism in NDDs, in which mitochondrial quality control failure, through impaired mitophagy, defective protein import, and ROS-driven dysfunction, links mitochondrial damage, mtDNA-mediated inflammation, and protein aggregation [68,69,70,71,72,73]
Increased psychiatric morbidity before and after the diagnosis of hypothyroidism: a nationwide register study
Lebers hereditary optic neuropathy (Vitamin B12 sensitive)
Unlike many other antioxidants that you must get solely from your diet, your body actually produces its own glutathione in the liver
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