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NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN)

Administered via subcutaneous injection, it crosses the blood-brain barrier to act on various regions of the hypothalamus, including the arcuate nucleus

Other Ingredients: Water, glycerin, ethanol, vitamin E (as tocopherols), natural flavors (lemon & mint), potassium sorbate (preservative)

All compounds referenced are supplied strictly for laboratory research use only

Measure carefully with a 3 mL syringe, not an insulin syringe which maxes out at 1 mL and would require multiple draws

Consequently, the tirzepatide group was reduced to three animals by the end of the study