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Moreover, rapid weight loss can affect your body in ways that are already in flux postpartum

If you are on a higher dose, say 7.5mg or above , the smaller injection volume means less liquid under the skin

doi: 10.1038/s41573-025-01231-3

Thus, expectations for the overall magnitude of effect from a given agent might be modest when treating patients whose baseline A1c is 30 pioglitazone reduced HbA1c levels better than sitagliptin while in individuals with a BMI 90 canagliflozin lowered HbA1c better than sitagliptin while in individuals with an eGFR between 60-90 sitagliptin was more effective (13)

Thyroid function tests should be monitored periodically during treatment, and levothyroxine doses adjusted as needed based on TSH levels and clinical symptoms

Sterling JK, et al