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However, the needle used is very fine, and the discomfort is minimal

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An ongoing autoinjector shortage might make it difficult to come by either of these branded medications.11 That may lead you to seek out compounded versions, but these often come in vials and require you to inject yourself with a traditional syringe

Louis Aronne is a paid consultant and advisory board member for Eli Lilly and Company, the study sponsor and the manufacturer of orforglipron and tirzepatide.