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10.1146/annurev.pharmtox.46.120604.141043 12 ChenM.-l.YiL.ZhangY.ZhouX.RanL.YangJ.et al (2016)

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BOX 7-3 Proposed Characteristics of Congenital Melanocytic Nevi That Increase Risk for Malignancy Size Number of medium CMN Location Number of satellite nevi by 1 year of age Heterogeneity of color Rugosity Hypertrichosis Extensive nodules Adapted from Krengel, S., Scope, A., Dusza, S.W., Vonthein, R., & Marghoob, A

75 These values can then be used to determine if a clinically significant response to treatment has occurred

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