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Additionally, the bias in patient selection across the literature raises the probability that improvements in systemic metabolic function, rather than direct immunomodulation, may underlie the observed improvements in psoriatic skin lesions

Staying hydrated and maintaining regular eating patterns may help support digestive comfort

Combining GLP-1RAs with anti-VEGF agents or IOP-lowering drugs may enhance efficacy but pose unresolved challenges

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3,4 Due to the overlap in chronic inflammatory pathophysiology, GLP-1 RAs may serve as a potential therapeutic candidate for the management of these skin disorders, particularly those co-occurring with metabolic dysfunction

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