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Under inflammation, glia cells become activated, leukocytes are recruited across the BBB, and the BBB itself breaks down, with alterations in paracellular and transcellular transport and tight junction protein expression [63,64,65,66,67]

[DOI] [PubMed] [Google Scholar] 38.Morscher E Etiology and Pathophysiology of Leg Length Discrepancies In Leg Length Discrepancy The Injured Knee

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8 Additionally, while TMAO affects endothelial barrier function, it can also act on various types of cells, including vascular smooth muscle cells, epithelial cells, pancreatic cells, neurons, astrocytes, microglia, and oligodendrocytes, thereby exerting broad impacts on numerous human diseases