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Clinical Considerations Fetal/Neonatal Adverse Reactions Amphetamines, such as VYVANSE, cause vasoconstriction and thereby may decrease placental perfusion

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This indicates that biologic LOE models must account for a 2-3 year ramp to peak erosion, rather than the 6-month crash of small molecules

Patients should be advised to take this medication as directed and to report any adverse effects or concerns to their healthcare provider promptly

The treatment's other benefits includes a reduction in liver disease and heart failure and you can read about it here

& Westerhof, W