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the study physician attributed the death to pre-existing coronary artery disease unrelated to the drug, but the FDA's Pharmacy Compounding Advisory Committee cited this "unresolved cardiac signal" in December 2024 as a reason to keep the compound off the approved compounding list

anaphylaxis, though rare, necessitates immediate discontinuation and emergency management

CagriSema is the only one with Phase 3 combo data and a pending FDA decision

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In addition, many dietary and pharmacological compounds also modify the intestinal Ca 2+ transport[20]