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In addition, for subjects with a 2-h pre-dose fast, increasing the length of the post-dose fast did not seem to affect the absorption of oral semaglutide, with similar exposure levels observed between the 2 h30 min and 2 hnight treatment arms, indicating that the disruption of semaglutide absorption caused by food components in the stomach at dosing cannot be compensated by longer post-dose fasting

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Exercise can also improve mood, which might reduce feelings of tiredness

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This precision approach may reduce unnecessary side effects and support safer, more effective therapy