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If your current medication plateaus or becomes less effective, discuss options proactively

It seems that obesity plays an important role in the pathophysiology of migraine as well, with obese women having elevated plasma levels of calcitonin gene-related peptide (CGRP) compared to controls [32, 33]

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Your clinician should explain both the benefits of GLP-1 therapyincluding improved glycaemic control, weight loss, and cardiovascular protectionand the theoretical risks based on animal data

The standard approach involves starting at the lowest dose and gradually increasing every 4 weeks to minimize side effects