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Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine

When you consume a substance orally, a percentage of that substance is metabolized by the body before it can actually get into the bloodstream

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We then purified pU L 31 using commercially available anti-HA agarose beads and examined the presence of DDX3X by Western blotting