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( Response: We refer readers to the more substantial discussion of these comments and our responses to these comments in section XIX

10.1016/j.micinf.2012.12.005 65 GugnaniK

Since BDP-12 differs from the aa 93-96 within the -turn of BDNF loop 4, which is the segment known to mediate TrkB activation and promote cell proliferation 19 , we guess that BDP-12 may avoid the pro-proliferative side effect, a key advantage for its development as an anti-inflammatory drug candidate

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