You can stop abruptly without dangerous withdrawal effects, but tapering down is recommended to maintain weight loss longer
Why Compounded GLP-1 Timing Differs From Natural Release PlexusDx compounded semaglutide injection provides stable, continuous GLP-1 activity rather than the pulsatile pattern of natural hormone release
Reubi JC, Schaer JC, Markwalder R, Waser B, Horisberger U, Laissue J
Even though GLP-1 medications improve blood sugar regulation, the reduced caloric intake they produce can occasionally cause blood sugar to drop too low, especially if you are also taking metformin
doi: 10.1007/s13679-025-00611-5
Summary Keywords glucagon-like peptide-1 receptor, Alzheimers disease, diabetes mellitus, insulin resistance, neuroinflammation Citation Li S, Huang N, Wang M, Huang W, Shi J, Luo Y and Huang J (2025) GLP-1R as a potential link between diabetes and Alzheimers disease