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Based on these promising research results, the therapeutic effect of the nanoreactors were studied in osteosarcoma bearing mouse models

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Alfenito et al, 1998), and naturally occurring endogenous reactive electrophilic compounds (Marrs, 1996), but may have then been recruited to detoxify anthropogenic exogenous xenobiotics (Kreuz et al, 1996

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The labile iron pool (LIP), particularly Fe 2 , enhances the formation of reactive oxygen species (ROS) during the Fenton reaction, thereby leading to ferroptosis