Sattar N, Verma S, Sourij H, Wilson J, Stefanski A, Zhang X, Griffin R (2024) Inflammatory biomarkers in people treated with tirzepatide living with overweight or obesity, without and with T2D: a post-hoc analysis from SURMOUNT-1 and SURMOUNT-2
More affordable than traditional GLP-1s
Patients may feel the medication works less dramatically over time because they have adapted to its effects
Managing Side Effects: A Practical Guide Understanding the side effect timeline transforms the experience from something that catches you off guard to something you can prepare for and manage proactively
GLP-1-induced intra-islet insulin secretion may locally inhibit glucagon secretion
Furthermore, an association was found between the degree of insulin resistance and impaired GLP-1 response [57]