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Of the 1,715 adult epileptic patients treated with topiramate at doses of 200 to 1,600 mg/day, 28% discontinued treatment because of adverse reactions which included sleepiness (3.2%), feeling dizzy (2.6%), balance issues (2.2%), paresthesia (2%), and language problems (2%)

Kayakers showed more pronounced gains in muscle carnosine in the deltoid muscle compared to the soleus and gastrocnemius, whereas the reverse pattern was seen in cyclists

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In 1963, the introduction of Allopurinol, an inhibitor of xanthine oxidase, marked a significant advancement in treating hyperuricemia

If side effects are troublesome, your healthcare provider can explore alternative management strategies or medications that may be better suited to your needs