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GLP-1 receptor agonists include semaglutide (trade names: Ozempic, Wegovy, Rybelsus)

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You can administer both compounds at caloric maintenance or surplus, but the metabolic shifts will be far less pronounced than in deficit states

In older adults, low circulating levels of vitamin D have been linked to increased lateral ventricle volume, a structural marker associated with brain atrophy and cognitive impairment