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Tanaka T, Okuda H, Isonishi A, Terada Y, Kitabatake M, Shinjo T, et al

They define PCOS as the presence of two out of three criteria: hyperandrogenism (elevated levels of male hormones, assessed clinically -presence of acne, hirsutism- or biochemically), ovulatory dysfunction (oligo/anovulation, infrequent or absent ovulation), and/or polycystic ovarian morphology on ultrasound: either the presence of 20 or more follicles on a single ovary or ovarian volume above 10 cm3

Ng FM, Jiang WJ, Gianello R, Pitt S, Roupas P

For example, injections of CJC-1295 produce GH levels that rise 2- to 10-fold and IGF-1 levels that increase 1.5- to 3-fold over baseline in humans for several days