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Clinical trials have demonstrated significant reductions in hemoglobin A1c levels (approximately 1.52.0% from baseline) and substantial weight loss (averaging 1015% of body weight with higher doses)

Because insurance companies tend to only cover prescriptions for their FDA-approved use, Blue Cross Blue Shield is more likely to cover Zepbound than Mounjaro for weight loss or sleep apnea, a recently FDA-approved use for Zepbound