Nearly all PCOS patients prescribed semaglutide or tirzepatide also had obesity or type 2 diabetes, suggesting use remains primarily tied to metabolic indications, though broader interest in PCOS benefits is growing within scientific literature
If a person responds to a lower dose with good weight loss, further dose escalation may not be needed, says Kushner
Proteins downregulated by GLP-1GIPLani (cluster 1) were mainly associated with calcium and tubulin binding, ion channel and phosphatase regulation and protein folding, whereas proteins upregulated by GLP-1GIPLani (cluster 3) were linked to oxidative and lipid metabolism, ribosomal activity and amino acid and carbohydrate metabolism (Fig
Peer review Peer review information Nature Reviews Rheumatology thanks Helena Marzo-Ortega, who co-reviewed with Jacob Williams
Alopecia associated with the use of semaglutide and tirzepatide: A disproportionality analysis using the FDA adverse event reporting system (FAERS) from 2022 to 2023
How to distinguish telogen effluvium from other types Telogen effluvium produces diffuse thinning across the entire scalp
