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Thus, it is likely that striatal rCBF changes during NPW reflect contributions from multiple neurotransmitters [77]

Duran, R

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Amyloid aggregates form when the membrane-bound amyloid precursor protein (APP) undergoes a series of proteolytic cleavages orchestrated by -secretase (beta-site APP-cleaving enzyme, BACE) and furthered by -secretase [50]