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The inflammasomes: guardians of the body

Rather than waiting passively for healing to occur, the peptide actively recruits the cellular machinery necessary for tissue regeneration

Similarly, in fibroblasts from 26-month-old C57BL/6 mice, GHK reduced p21 and p53 expression (Figure 2B), further supporting its role in suppressing the senescent phenotype

The anti-inflammatory action of ghrelin occurs mostly via the inhibition of the NFB pathway [240,241], and not by scavenging intracellular ROS [226] even if ghrelin has antioxidant properties [228,233,242]

Navarro-Alarcon, M., de la Serrana, H

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