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I just started picking up a few pounds every year, and so I pick up a few pounds and then you stop playing in the softball league, and then you pick up a few pounds and then you stop playing in the volleyball league, and then you pick up a few pounds and you realize you're staying in the recliner instead of getting out and playing with the dogs or attending your kids functions and things like that

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Liver Enzyme Interactions Berberine is processed by the liver and can interfere with certain enzymes (specifically the CYP450 pathway) that are responsible for breaking down other medications