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Vomiting or diarrhea: Temporary gastrointestinal symptoms that usually improve as the body adapts

Once you reach steady state (typically by week 56), your weight-loss rate should stabilize at 13 pounds per week on average

By activating this pathway, retatrutide helps smaller portions feel sufficient, curbs snacking urges and keeps energy levels steady throughout the day

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By targeting these fibres directly, Pure Impact helps maintain functional muscle, supporting metabolism, posture, and the structural integrity of the body during weight loss

In the 12 mg arm, participants achieved a mean body weight reduction of approximately 24% at 48 weeks the highest observed across the dose groups though this arm was also associated with a higher incidence of gastrointestinal side effects