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298H1155H1165

10.1186/s12872-023-03603-2 41 LinL.YangL.WangN.ChenS.DuX.ChenR.et al (2024b)

Standard technique involves using 29 to 31 gauge insulin syringes with 1/2 inch needles for subcutaneous administration

Surprisingly, unlike systemic Klotho deletion, its specific depletion from osteocytes may dramatically increase bone formation and Klotho overexpression in osteoblastic cell-suppressed bone mineral formation and osteogenic activity (Komaba et al., 2017)