Animal Model:High fat diet-induced obesity mouse model [3] Dosage:50 mg/kg Administration:i.p., twice per day for 28 days or 12 days Result:Did not alter brown adipose tissue mass, daily food intake and glucose metabolism, increased fatty acid oxidation (FAO) in normal in C57Bl/6 mice, but induced a progressive weight loss and decreased adipocytes size in high fat diet-induced obesity mouse models
Severe or frequent hypoglycemia is an indication for the modification of treatment regimens, including setting higher glycemic goals
overactivation of PARPs, such as during extensive genotoxic stress, can result in significant NAD + depletion and subsequent compromise of cellular energy homeostasis
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Supplied as a solid research compound for in-vitro laboratory and analytical research use only