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*Correspondence: Ke Jiang, [email protected] Zheng, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Laboratory assays often measure these effects using: cyclic AMP reporter systems kinase phosphorylation analysis transcriptional profiling These approaches help researchers examine how multi-receptor signaling alters intracellular signaling dynamics

Demonstrate pen use and have patients perform return demonstration

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