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Glucagon-like peptide-1 (GLP-1) is synthesized by enteroendocrine L cells in the intestine and by specialized neurons in the nucleus tractus solitarius [3]

The FDAs position is straightforward: once a medicine is past the date on the label, you shouldnt use it because its strength and safety are no longer guaranteed, and that includes sildenafil, as the agency warns in its page on using expired medicines

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Tebon PJ, Wang B, Markowitz AL, Davarifar A, Tsai BL, Krawczuk P, et al

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