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The molecule was developed by Frank Ng's group at Monash University and Metabolic Pharmaceuticals in Australia during the 1990s and 2000s as a potential anti-obesity drug intended to isolate the lipolytic region of hGH without activating the growth hormone receptor or raising IGF-1.nnIn published preclinical work, the fragment has been shown to stimulate lipolysis, suppress lipogenesis, and modulate the beta-3 adrenergic receptor pathway in adipose tissue rather than acting through the classical hGH receptor

PMC 6543499

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higher doses require split injections) 12 weeks: 1224 syringes 24 weeks: 2448 syringes Bacteriostatic Water (10 mL bottles): Use ~2.0 mL per vial for reconstitution

And of the few that exist (less than 10), they are either done in cell cultures or in rats

The peptide stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) in adipose tissue