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(55) found that in a mouse model of corneal alkali injury, the expression of ROS was upregulated, oxidative stress increased, the expression of the gene Ptgs2, a key marker of ferroptosis, was elevated, the level of the lipid peroxidation product 4-hydroxynonenal (4-HNE) increased, and the level of the ferroptosis regulator GPX4 decreased, with mitochondrial damage

[PMC free article] [PubMed] [Google Scholar] 25.Streit M, et al

PLoS ONE 9 , e104519 (2014)

Use as context, not proof

Safety and tolerability of the dual 5alpha-reductase inhibitor dutasteride in the treatment of benign prostatic hyperplasia

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