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Both secondary metabolites also suppressed the TPA-activated DNA binding activity of NF-B when applied topically on mouse skin (Chun et al., 2002)

Same results were obtained on culture models, the P e values of ibuprofen were 0.28 and 0.53 10 6 cm/s across a porcine brain endothelial cell line and a rat primary brain endothelial based BBB models, respectively [71]

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Additionally, Minuk and Lewkonia (1986) have even reported familial clustering of Inflammatory Bowel Disease (IBD) and MS, suggesting that they have genetic or environmental risk factors in common

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Cancer Cell 9, 425434