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Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons

Various oral antidiabetic drugs, including metformin, sulfonylureas, meglitinides, alpha-glucosidase inhibitors, thiazolidinediones (TZDs), DPP-4 inhibitors, and GLP-1 receptor agonists, lower blood glucose through mechanisms such as enhancing insulin sensitivity, stimulating insulin secretion, and slowing carbohydrate absorption

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Alterations in the gut microbial community can therefore significantly impact host lipid metabolism and cardiovascular risk