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The resulting iron ions then circulate in the plasma as Fe 3+ , binding with transferrin (Tf) to form iron-transferrin complexes ( 3+ from Tf, which is then reduced to Fe 2+ by prostate six transmembrane epithelial antigen 3 (STEAP3) ( The gut exhibits precise regulation of iron homeostasis

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Systemic absorption is minimal

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Author contributions MA: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Methodology, Project administration, Validation, Writing review and editing