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Neurotoxic reactive astrocytes are induced by activated microglia

Al-Qaraleh SY, Al-Zereini WA, Oran SA, Al-Sarayreh AZ, Al-Dalain SM

& Haeussler, M

When the redox balance is disrupted, excessive production of free-radicals start to cause significant damage as the body is left unable to counteract the overproduction of these oxidant agents

In that trial, diarrhoea was reported in approximately 2030% of participants receiving higher doses of retatrutide, with rates varying by dose level and stage of titration

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