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While we still need more data, I think GLP-1s deserve a place in the conversation for patients with PCOS, insulin resistance, or obesity who are struggling to conceive.

In terms of sensitivity, excluding published before 2002 and smaller studies also showed no obvious change in the primary outcomes

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The newer high-dose semaglutide 7.2 mg (Wegovy, STEP UP trial) achieved 18.7%

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Similarities between the medications As mentioned earlier, both medications are used for treatment in type 2 diabetes and obesity but the efficacy varies