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Kulijewicz-Nawrot, M., Verkhratsky, A., Chvatal, A., Sykova, E

Development of a reactive oxygen species (ROS)-responsive nanoplatform for targeted oral cancer therapy

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shows that hesperetin diminish the maturation and function of monocyte-derived dendritic cells in asthmatic patients via inhibiting NF-B activation, decreasing IL-4 levels, and increasing IFN- production, thus attenuating airway inflammation and airways remodeling though reducing fibrosis and mucus plug formation (Gu et al

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The study found that the three natural inhibitors exhibited distinct binding orientations when interacting with hTYR and mTYR