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Side Effect 5: Systemic Effects Systemic reactions may include fatigue, anxiety, and numbness in extremities

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PMC 2775832

As we get older, our skin continues to lose hydrating properties that lead to the development of fine lines, wrinkles, and volume loss

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Furthermore, another comparison of patients who had continuous use of statins with the patients who did not use any cholesterol-lowering drugs showed that statin use was associated with lower risk of abnormal depression scores, anxiety, and hostility, after adjustment for the propensity for statin use and potential confounders