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In fact, lower IRRs were observed during both the initial (012 months) and late (1324 months) exposed periods compared with pretreatment, a pattern also seen for SGLT-2 and DPP-4 inhibitors, possibly reflecting increased healthcare contact or a healthier lifestyle during treatment

Andersen ML et al

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The science of gut microbiome and metabolic health: why this matters To truly evaluate whether a postbiotic supplement like resM can influence your metabolism, you need to understand the rapidly evolving science connecting your gut bacteria to your metabolic function

32 , e4619 (2023)

The article frames those as provider decisions arranged in advance for higher-risk patients, not as something to add on your own