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Positive regulators of ferroptosis Given the intricate connection between the ferroptotic process and oxidative stress-induced lipid peroxidation, the synergistic interplay of ROS amplification, lipid provisioning, and activation of lipid peroxidation enzymes collectively contribute to fostering ferroptosis induction or augmenting ferroptosis sensitivity (Fig
The increased colocalization between SERCA2a and LC3 in the presence of lysosomal inhibitors implies that autophagy may regulate trafficking of SERCA2 through modulation under TMAO stimulation
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