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Conclusion GLP-1 agonists are pivotal in managing type 2 diabetes and supporting weight loss by mimicking natural hormonal actions that regulate insulin, glucose, and appetite

In addition to boosting GLP-1, the GLP-1/GIP agonist tirzepatide (Zepbound) mimics the hormone gastric inhibitory polypeptide (GIP), which has similar effects to those of GLP-1

Global and societal implications of the diabetes epidemic

Key Takeaways: GLP-1 use among patients newly diagnosed with Polycystic Ovary Syndrome (PCOS) without type 2 diabetes rose 6.7-fold between 2020 and 2024

INCIDENT DESCRIPTION A patient who was taking semaglutide injections once weekly for weight loss underwent orthopedic surgery

doi: 10.1172/jci.insight.133429 171 ZhangFTongYSuNLiYTangLHuangLet al