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Psoriasis fundamentally arises from the interaction between the innate and adaptive immune systems, particularly including T-cells, dendritic cells, and pro-inflammatory cytokines (Schon & Erpenbeck 2018) (Fig

Its pivotal position in ferroptosis regulation highlights its importance as a therapeutic target for OA and other ferroptosis-driven diseases

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One particularly serious concern is acromegalic cardiomyopathy, enlargement and weakening of the heart

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