Zalfa C, Paust S
In that regard, the transcription factor NRF2 (nuclear factor erythroid 2-related factor 2) and its main negative regulator KEAP1 (Kelch-like ECH (erythroid cell-derived protein with CNC homology)-associated protein 1) represent a finely regulated antioxidant system, with a key role in the response to OS and maintenance of redox homeostasis
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Use clean personal care products, filter your drinking water, and aim for consistent, high-quality sleep to give your body time to reset its redox balance
In transsulfuration, the disposal of homocysteine is catalyzed by the B6-dependent cystathionine -synthase, which leads to cystathionine and subsequently to cysteine and GSH biosyntheses (Figure 3)
While most of the cysteine for glutathione was derived from exogenous source in nutrient replete culture, serine-derived cysteine may become more important under nutrient-limiting conditions
