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Clinical trials may be warranted to explore the potential use of naltrexone in people with these debilitating illnesses which currently have no licensed treatments available

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This is partially because advocates want the latest medications available to the Medicare population, but also because they believe private insurers might follow Medicares lead

This can be due to excess histamine from food, producing too much histamine, or not being able to break it down efficiently

Research from the University of Oxford found that those who stop regain weight steadily, returning close to their original size within approximately 1.7 years [BMJ, 2026]