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Data availability The raw data generated from this study including RNA-Seq has been deposited in SRA (accession number: PRJNA1183441, Source data are provided with this paper

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Each formulation is built around a defined logic: components are selected based on their documented mechanisms of action in preclinical literature, and the resulting combination addresses complementary biological pathways within a single preparation

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However, there are potential inhibitors of SCC that target aberrations in cells

In addition, there was also a study indicated that the combination of baicalin and interferon -2b could improve the sera negative transformed rate and protect liver cells from inflammation and prohibitive liver fibrosis (Song et al., 2013)