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Kligman AM (1966c) The SLS provocative patch test in allergic sensitization

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Common (Oral): Gastrointestinal disturbance, diarrhea, nausea, vomiting, fatigue, conjunctival irritation, skin rash (26) (28) Other: Hypotension, anaphylaxis, asthma attacks, headache (29) Case reports Photosensitivity not attributable to location, season, or concomitant medication: Occurred among pulmonary fibrosis patients more frequently with acetylcysteine than placebo in combination with pirfenidone (39)

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This could lead to unpredictable reactions beyond just skin issues