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Effective at reducing of dark spots, acne scars, hyper-pigmentation and other forms of melasma

In patients with overweight or obesity (mean age 50.1 years, 72.6% female), semaglutide compared with non-GLP1R agonist anti-obesity medications was associated with lower risk for incident (HR = 0.27, 95% CI = 0.200.320.600.36) and recurrent (HR = 0.44, 95% CI = 0.320.60) suicidal ideation, consistent across sex, age and ethnicity stratification

Neither scenario is what the retatrutide dosing protocols were designed around

The research utilized male Sprague-Dawley rats and various in vitro and ex vivo experimental models [1]

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