Glutathione is a triple-threat molecule made of three specific amino acids: cysteine, glutamate, and glycine
Delmulle T, Bovijn S, Deketelaere S, Castelein M, Erauw T, Dhooghe M, Soetaert WK (2023) Engineering Comamonas testosteroni for the production of 2-pyrone-4,6-dicarboxylic acid as a promising building block
Together, these results indicate that the antioxidant action of -glutamylcysteine takes place regardless of GSH concentrations, thus cannot simply rely on its ability to replenish GSH, as it can be seen in other paradigms 19
10.1016/j.pneurobio.2011.06.003 Prog
However, human protocols typically employ milligram-range dosing to achieve systemic effects
[20] Cancer [edit] Many different kinds of cancers have been observed to contain mutations that promote AKT phosphorylation, and thus the inactivation of FOXOs, effectively preventing proper cell cycle regulation