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In lab models, DSIP potentiated GABA-activated currents and affected excitatory signaling, which aligns with its studied calming/sleep-related effects
Many of the previous studies had methodological limitations such as selection bias [10, 12], and limited generalizability [11, 29]
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The lack of therapeutic innovation in the bipolar disorder field is largely due to a poor understanding of the underlying disease mechanisms and the consequent absence of validated drug targets
Parallels with berberine, natures Ozempic The findings also reveal unexpected parallels with berberine, a popular plant-derived, over-the-counter supplement often used to control blood sugar