Copper peptides have good tolerance and are considered safe for topical use
Pneumonia (Nathan Qld.) , 13 (1), 7
It also operates as an essential cofactor for various enzymes and plays a pivotal role in several important metabolic functions 3,4,5 including: Biochemical foundation of P450 enzyme detoxification in the liver, lungs, kidney and intestinal epithelia Participates in converting drugs and other toxic chemicals more water-soluble for easier excretion Participating in antioxidant defence systems Protection against free radicals Primary protectant of lens, cornea, skin and retina against radiation damage Regulating and maintaining cellular redox balance Helping metabolise oestrogens and inflammatory compounds Storing and transporting nitric oxide Storing cysteine reserves Regulating the function of proteins Involvement in DNA synthesis Participating in iron and copper transfer Glutathione tends to be found in high concentrations in all cells of the human body, particularly the liver

However, more studies are needed to compare different forms of glutathione supplementation to determine the most effective method
10.1002/ana.10517 256 WangY.-M.CuiQ.-F.ZhaoW.-L.ZhangJ.-Y.WangH.-Q
Previously we showed that RAP guanine exchange factors EPAC1/2 (Exchange Proteins Activated by cyclic AMP) promote the growth of primary melanoma and loss of dependency on EPACs is associated with metastatic progression